Celebrities with Angelman Syndrome

17 Interesting Facts About Angelman Syndrome + Famous Peopl

Actor Colin Farrell and his ex-partner Kim Bordenave have been quite open about the condition that has afflicted their son, James Farrell, who has been diagnosed with Angelman Syndrome. News.. Colin Farrell's son, James, suffers with Angelman Syndrome The syndrome is characterised by the inability to speak, balancing disorders, seizures and retarded development and anyone suffering with the disorder will require full-time care throughout their life Turning 14 this year, Colin Farrell and Kim Bordenave's son James is certainly a special, and rare, case. Colin addressed the media in October of 2007 and reported that his son suffered from Angelman syndrome. How common it is remains unknown. Some studies have pegged it at 1 in 24,000 while others claim it's twice as likely as that Actor Colin Farrell's son, James, has Angelman syndrome. In a piece for Darien Patch he said, [James] has made my life so much richer and so much more worthwhile and has given it such meaning..

Colin Farrell talks about son with Angelman Syndrome

Famous people with Angelman syndrome The sons of the following famous personalities have been diagnosed with Angelman syndrome: Collin Farrell a Hollywood actor, Ian Rankin an author, Dave Henderson a professional baseball player, and Peter McDuffe a professional hockey player Angelman syndrome is a complex genetic order that mostly impacts the nervous system, according to Medline Plus. It can lead to developmental delays, intellectual disability, severe speech. But Cecilie is 12 years old and suffers from Angelman Syndrome, a complex genetic disorder that primarily affects the nervous system. Characteristic features of this condition include developmental delay, intellectual disability, speech impairment, and problems with movement and balance. Cecilie was born very small, about 2.5 kg Famous people with Angelman Syndrome James Farrell, the four year old son of Hollywood actor Collin Farrell suffers from this disorder. Other famous Angelmans Syndrome patients include sons of prominent personalities like hockey player Peter McDuffe, baseball pro Dave Henderson and writer Ian Rankin. Picture 3 - Dave Henderso In honor of International Angelman's Day on Feb. 15, celebrities with personal connections to the disease - Farrell's son and Retta's godson both have it - are participating in a video.

Who is James Farrell? Colin Farrell gave up drugs and

  1. Actors Colin Farrell, Jai Courtney, Josh Peck, Retta, Zachary Levi and Jesse Lee Soffer are among those expected to attend the event benefiting the Foundation for Angelman Syndrome Therapeutics..
  2. Angelman syndrome or Angelman's syndrome (AS) is a genetic disorder that mainly affects the nervous system. Symptoms include a small head and a specific facial appearance, severe intellectual disability, developmental disability, limited to no functional speech, balance and movement problems, seizures, and sleep problems. Children usually have a happy personality and have a particular interest.
  3. Here are some celebrities with special needs kids that you might not know about. 1. Katie Price. Model Katie Price is mom to Harvey. Harvey was born in 2002 and was diagnosed with Prader-WIlli syndrome (a genetic condition caused by the loss of certain genes), Autism, and blindness

What is Angelman Syndrome? Colin Farrell's son diagnosed

Angleman, Rett, and Prader-Willi Syndromes. By Doug Gillett. Angelman syndrome affects one in every 10,000 to 12,000 births. Prader-Willi syndrome, at one in 12,000-15,000 births, is even rarer. Rett syndrome affects one in every 12,500 female births. Clearly, one of the biggest challenges in learning more about these diseases is simply finding. Angelman syndrome is a hereditary condition caused due to presence of errors in the UBE3A/ubiquitin-protein ligase E3A gene which occurs on chromosome 15. It is known that genes are passed on from the parents in pairs, wherein one copy is inherited from the father while the other is given by the mother. In most cases, both the copies of genes. Key Facts about Angelman Syndrome. The syndrome is caused by missing or altered genetic information on the maternal copy of chromosome 15. Mobility in Angelman syndrome appears to be related to the genetic cause. Individuals with Angelman syndrome are often described as having very happy and excitable personalities and parents often report that. The Total Recall actor's eldest child James, nine, suffers from Angelman Syndrome - a neuro-genetic disorder with symptoms including intellectual and developmental disability, seizures, jerky. However, he did not clearly exhibit any of the other clinical features typical of the syndrome. READ MORE: Celebrities With PTSD. 11) Arik Einstein. He was a vocalist for Shleeshiyat Gesher Hayarkon (Yarkon Bridge Trio), Batzal Yarok (Green Onion), and Hahalonot Hagvohim (The High Windows). Arik had Marfan Syndrome

Colin Farrell has filed for conservatorship of his 17-year-old son, James Farrell, who has been diagnosed with Angelman Syndrome. According to the court petition obtained by E! News, Colin and. Angelman syndrome is caused by the loss in function of a single gene, UBE3A, on Chromosome 15 which is vital to how the brain controls speech, movement and l..

Colin Farrell talks about his son's life with Angelman

Angelman syndrome is a genetic condition that affects the nervous system and causes severe physical and learning disabilities. A person with Angelman syndrome will have a near-normal life expectancy, but they will need support throughout their life. Characteristics of Angelman syndrome Those with Angelman syndrome has a common characteristic of being abnormally fascinated with water which can lead to an increased risk of drowning. Angelman Syndrome Life Expectancy. For those with Angelman syndrome who live an active and healthy lifestyle the life expectancy is the same as normal individuals. This disorder has not been found. No: As is a genetic disorder due to dysfunction of a gene (ube3a) on chromosome 15. Patients have developmental delay, problems with movement/balance, happy/excitable personality & problems with speech.See: www.Angelman.Org. The children of some famous people have been diagnosed with as: sons of actor, colin farrell, author, ian rankin, baseball player, dave henderson, & hockey player, peter.

Angelman syndrome is a genetic disorder that causes developmental delay and neurological problems, affecting between 1/10,000 and 1/20,000 children and young adults. A physician named Harry. Famous People with Angelman Syndrome The Son of Colin James Farrell James Farrell is one of the most of popular and best foreign actors in Hollywood. baseball player Dave Henderson and professional hockey player Peter When did organ music become associated with baseball? When he was 10 years old, his family moved to Castle knock. 2012-03-27 00.

Celebrity News. Published May 12. Colin Farrell files for conservatorship of son with Angelman syndrome Farrell and his ex are due in court on Sept. 27. James has Angelman syndrome, a genetic. Oct 3, 2014 - Explore Wendy Wines's board Angelmans Syndrome on Pinterest. See more ideas about angelman syndrome, syndrome, rare genetic disorders

Apr 3, 2019 - Explore Jessica Cicalli's board Special Needs / Angelman Syndrome, followed by 239 people on Pinterest. See more ideas about angelman syndrome, special needs, syndrome People with Angelman Syndrome have a normal life expectancy providing that there are no medical complications. They can live a happy and active lifestyle if they have a good support network. Many adults with AS live independent of their families in their own homes with support or in a residential environment. Adults with AS usually [ Hollywood celebrities will be out in force tomorrow at a Chicago gala to help raise awareness and money for the debilitating disorder, Angelman syndrome. Actors Colin Farrell, Jai Courtney, Josh. Colin Farrell just took a big step when it comes to supporting one of his children. As reported by E! News, Farrell has filed for co-conservatorship of his 17-year-old son James Farrell, who has Angelman syndrome.James' mother, model Kim Bordenave, has filed to be his other conservator Celebrity supporters of Foundation for Angelman Syndrome Therapeutics, including Colin Farrell, Rosie Perez, and Retta. We have 3 articles about past events, donations and campaigns

13 Celebs You Didn't Know Have Special Needs Kids BabyGag

Angelman syndrome is a rare genetic disorder that causes developmental disabilities and nerve-related symptoms, writes Angelman.org. It is not detected in a child until a baby turns between six to twelve months old. Symptoms include lack of crawling or babbling, minimal speech, and frequent smiling and laughter Angelman Syndrome is a neuro-genetic disorder that affects [] Bubba 'Hightower' Smith died aged 66 Charles Aaron 'Bubba' Smith, winner of the 1971 Super Bowl and later starring as 'Moses Hightower' in the Police Academy movies died aged 66 Angelman Syndrome is a genetic disorder effected by a deletion or mutation on the 15th chromosome on the part received from the mother. Dan (2009) studied mice with a missing or mutated section of the 15th chromosome. The affected mice had impaire Colin Farrell is quite a famous actor. He has a son with a very rare genetic disorder called Angelman Syndrome. I have worked with a person with this exact diagnosis who had many of the symptoms listed in the article below

James Padraig Farrells age is 17 years as of 2021.. According to the source, he was born on September 12, 2003, and his zodiac sign is Virgo. Additionally, he was born in LA, California, which means his nationality is American.. James Has Angelman Syndrome The actor, 44, is petitioning an LA court, alongside Kim, to put 17-year-old James - who has Angelman syndrome - in a conservatorship. Angelman syndrome is a rare neuro-genetic disorder that. By Korin Miller. May 12, 2021. Actor Colin Farrell has requested a conservatorship for his son, James Farrell, who has a rare genetic disorder known as Angelman syndrome. According to court. The Total Recall star filed for conservatorship of his 17-year-old son, James Farrell, who has been diagnosed with Angelman Syndrome — which the Irish star described in the filing as a genetic disorder which causes developmental delays and disabilities and affects the nervous system.. In the court petition, Colin and James' mother, model Kim Bordenave, are requesting to be co. Angelman syndrome is a genetic disorder and is caused because of the deletion of the chromosome fifteen from the chromosome set that is gotten from the female. This reason is seen in approximately sixty-eight percent of cases of Angelman syndrome. It can also happen occasionally if the fetus gets two copies from the male of chromosome fifteen.

Human Phenotype Ontology, a standardized vocabulary of phenotypic abnormalities encountered in human disease. With unmatched depth it enables clinicians to record and analyse data with extremely accurate computer interpretable ontology terms. Developed by The Monarch Initiative Angelman syndrome can affect any racial group or ethnicity. Symptoms usually begin to be noticed when children are between 6 to 12 months of age. How common is Angelman syndrome? Angelman syndrome affects one in every 12,000 to 20,000 children born. The syndrome affects both males and females equally Angelman syndrome is an otherwise genetic disorder that is characterized by happy, laughing person. Primarily, they have issues with development, often have seizures due to epilepsy, problems with speech and movement, and a short attention span. Their facial features are very distinct to the disease Other famous people with Angelman syndrome are Ian Ranking, the author, professional basketball player Dave Henderson and Peter McDuffe (professional hockey player) who has son with Angelman Syndrome. Angelman Syndrome pictures. Sponsored link. Related posts: Williams syndrome Angelman syndrome is a genetic disorder. It causes delayed development, problems with speech and balance, intellectual disability, and sometimes, seizures. People with Angelman syndrome often smile and laugh frequently, and have happy, excitable personalities

Colin Farrell has filed for conservatorship of his 17-year-old son, James Farrell, who has been diagnosed with Angelman Syndrome. According to the court petition obtained by E! News, Colin and model Kim Bordenave, who is James' mother, are requesting to be co-conservators of his person in a limited conservatorship. The legal arrangement allows the conservators to manage the personal needs. Angelman Syndrome Collection Showcase - Home. The Angelman Syndrome Collections Showcase was founded by Joanna Marcella to raise awareness and funds for Angelman Syndrome. This is a new site that will be used over the coming months to document in image format the journey of this Angelman Syndrome campaign. The slide show includes images the AS. James Age: How Old is The Celebrity Kid? James Padraig Farrells age is 17 years as of 2021. According to the source, he was born on September 12, 2003, and his zodiac sign is Virgo. Additionally, he was born in LA, California, which means his nationality is American. James Has Angelman Syndrome What is Angelman Syndrome? (Happy Puppet Syndrome) - Overview, Symptoms, Causes, Treatment, and Prevention. Learn more: https://healthery.com/health/angelman..

Prader-Willi syndrome (PWS) is a genetic condition that affects many parts of the body. Infants with PWS have severe hypotonia (low muscle tone), feeding difficulties, and slow growth. In later infancy or early childhood, affected children typically begin to eat excessively and become obese.Other signs and symptoms often include short stature, hypogonadism, developmental delays, cognitive. Williams syndrome is caused by a missing piece (deletion) of genetic material from a specific region of chromosome 7.The deleted region includes more than 25 genes. CLIP2, ELN, GTF2I, GTF2IRD1, and LIMK1 are among the genes that are typically deleted in people with Williams syndrome. Researchers have found that the loss of the ELN gene is associated with the connective tissue abnormalities and. Apert syndrome is a rare genetic condition that is apparent at birth. People with Apert syndrome can have distinctive malformations of the skull, face, hands, and feet. Apert syndrome is characterized by craniosynostosis, a condition in which the fibrous joints (sutures) between bones of the skull close prematurely The 2020 FAST Global Virtual Summit & mini-Gala, Virtually Unstoppable, will be a truly incredible virtual experience that you will not want to miss!As in prior years, the annual event will feature a science summit with updates on the latest Angelman syndrome (AS) research and clinical trials, AS specific educational workshops that give caregivers, therapists, and teachers valuable tools to. Bella was born with Angelman Syndrome. Mom: (ME) Crystal B. Dad: Bert B. She was born at UNC Hospital in 2009. Three years later, we went back to that same hospital just to find out our beautiful daughter has Angelman Syndrome and so our sto..

Angelman syndrome is a rare genetic disorder caused by issues with the UBE3A gene on chromosome 15. The UBE3A gene contains the information necessary for cells to produce the ubiquitin-protein ligase 3A enzyme. This enzyme plays a role in a pathway that labels proteins so cells can break them down Angelman syndrome is a genetic disorder with severe neurological problems. It is characterized by developmental delays, impaired balance and coordination, learning challenges, and speech difficulties. Babies may also have a small-sized head with a flattened back. 39 celebrities who are helping normalize breastfeeding Angelman syndrome (AS) is a neurogenetic disorder which causes delayed development, challenges with speech, balance, learning, and memory. Most people with AS also experience seizures. The annual FAST Global Summit & Gala features a science summit, educational workshops, AAC carnival and a star-studded gala recognized as Chicago's largest celebrity fundraiser

*Angelman syndrome facts medically edited by: Melissa Conrad Stöppler. Angelman syndrome is a genetic disorder with characteristic features that include severe speech impairment, developmental delay, intellectual disability, and ataxia (problems with movement and balance).; Angelman syndrome is named after the physician Harry Angelman who first delineated the syndrome in 1965 The sister genomic imprinting syndrome, Angelman syndrome, is due to loss of maternal expression of genes in the same region that are normally silenced on the paternal chromosome 15. An ideogram of chromosome 15 and order of genes in the 15q11-q13 region is shown in Fig. ( 2 2) Welcome! Log into your account. your username. your passwor Angelman syndrome is caused by the lack of a protein called E6AP, that is made by a gene called ubiquitin-protein ligase E3A (UBE3A).The UBE3A gene is part of a group of genes that are imprinted.Typically, our bodies use both the maternally-inherited and paternally-inherited copy of our genes to make whatever that particular gene's product is, like an enzyme or a protein Angelman syndrome is a genetic disorder that causes intellectual and developmental delay, seizures, frequent laughter, and ataxia, or poor control of voluntary movements.. Now, it happens when a gene on chromosome 15 called UBE3A is not expressed, or transcribed into messenger RNA. UBE3A stands for ubiquitin-protein ligase E3A, and the protein it codes for is called E6AP or E6-associated protein

20 Celebrity Dads Who Have Kids With Disabilitie

  1. Angelman syndrome is a genetic disorder, as is Down syndrome. But they are not the same. Angelman Syndrome involves a deletion of Chromosome 15, whereas people with Down syndrome have an extra.
  2. James has Angelman syndrome, a genetic disorder that is often first noticed when babies and young children have developmental delays.According to the Mayo Clinic, it causes delayed development.
  3. Young James' Rare Genetic Disorder Called Angelman Syndrome. Little James was born with a rare genetic disorder called Angelman syndrome, which is a developmental disability. The disorder is characterized by seizures, jerky movements, and sleeping problems. Furthermore, it is often misdiagnosed as autism or cerebral palsy
  4. James Padraig Farrell is a celebrity kid who is popularly known as the firstborn child and the oldest son of Irish actor Colin Farrell with his ex-girlfriend Kim Bordenave. Keep reading to discover more interesting information about James Padraig Farrell such as his age, Instagram, Angelman syndrome, photos, 2018, 2019, 2020, now, photos, Kim Bordenave
  5. g to terms with having a disabled child must be difficult but these celebrities have gushed at how proud they are of their kids and some say they wouldn't change their situation.
  6. The Foundation for Angelman Syndrome Therapeutics is pleased to announce the 3rd Annual FAST Gala, an Evening With The Stars To Benefit The Angels, a black tie fundraiser for Angelman.
  7. Angelman syndrome is a genetic disorder that affects the nervous system and causes severe physical and intellectual disability. A person with Angelman syndrome will have a near-normal life expectancy, but needs looking after for the rest of their life

How Colin Farrell Helped a Mom Understand Her Son's Rare

  1. James Padraig Farrell is widely known as the son of Irish actor Colin Farrell. He is of Irish and Polish descent. His parents are actor Colin Farrell and model Kim Bordenave. The couple has already separated ways after their son's birth
  2. After that, the actor was in a relationship with model Kim Bordenave. In 2003, the former couple welcomed their first and only son, James, who has Angelman Syndrome. As the Mayo Clinic explained, the syndrome is a genetic disorder that impacts the patient's speech, balance, and intellectual ability. The first time Colin spoke about his son's.
  3. e: 1) If a 15q11-13 deletion was transmitted from a female with Angelman syndrome to her fetus, and 2) If the UBE3A gene was functionally imprinted in fetal eye. Methods.
  4. As the father of a son with Angelman syndrome, Farrell supports the Foundation for Angelman Syndrome Therapeutics. He is an active supporter of several charities, and he is a UN Spokesperson in the war on hunger as well as the official games spokesman for the Special Olympics World Games in Shanghai, China

The FAST Gala is a one-of-a-kind experience and the highlight of the Angelman community. Come join us for an unforgettable evening of celebrities, entertainment, dining, dancing, celebration, hope, and friendship. Together we #CantStopWontStop bringing hope and going further faster to CURE AS! OUR SOLE MISSION: CURE ANGELMAN SYNDROME Colin Farrell's first-born son, James, has been diagnosed with Angelman Syndrome. This is a rare neuro-genetic disorder that results in developmental delays, impaired balance, and seizures. Currently, there is no cure for this condition. It is often misdiagnosed as cerebral palsy or autism Colin Farrell and Kim Bordenave File for Conservatorship of 17-Year-Old Son James With Angelman Syndrome. Stars — They're Just Like Us! Colin Farrell and former girlfriend Kim Bordenave. Many Angelman syndrome patients have delayed physical and mental development, making accidents and injuries more frequent and possibly reducing lifespan. Planning for the future. For most parents, it is likely their child with Angelman syndrome will outlive them. Because Angelman syndrome is a lifelong condition, your child likely will need.

Photo Gallery - Angelman Syndrome Foundatio

The RED GALA is a CASS fundraising event intended for all those who may play an active role in the Angelman syndrome community, whether it be corporate sponsors, families, or friends. One thing that is certain is that you will have the excuse to dress formally, experience a grand hotel with a high level of service, rub elbows with a celebrity. In addition to severe developmental delays, Angelman syndrome is characterized by a movement or balance disorder, ataxia, which can vary from mild to severe. Affected children demonstrate an apparent happy demeanor and hypermotoric behavior. Children with Angelman syndrome have severe to profound communication impairments Angelman syndrome is a sister of Prader-Willi syndrome, in which genetic disorder material is obtain or inherits from the maternal side but in the same region. The Angelman syndome (AS) is a neuro-genetic condition characterized by delayed development of mental and physical structures, sleep disturbance, seizures, always smiling and laughing and always in a happy mood condition, thus it. According to the Angelman Syndrome Foundation, the rare neuro-genetic disorder occurs in one in 15,000 live births or 500,000 people worldwide

Celebrities with Angelman Syndrome - Diseasemap

Angelman Syndrome. Angelman syndrome is a genetic disorder that affects the nervous system. Initial symptoms of this disorder typically manifest in the first year of life and become more apparent through early childhood. It is estimated that Angelman syndrome occurs in roughly every one in 15,000 people Here are the top interesting facts about Angelman syndrome: 1 Angelman syndrome (AS), which used to be called the happy puppet syndrome, is a rare genetic disorder with characteristic features that include - severe developmental delay, tremulousness with jerky movements of the legs and arms, severe speech impairment, inability to coordinate voluntary movements, and intellectual disability

Angelman Syndrome Current Health Advice, Health Blog

The Basics Name: Paula Evans. Title: Founder and Chairperson. Organization: Foundation for Angelman Syndrome Therapeutics (FAST) Social Media Links: Disease focus: Angelman syndrome (AS) is a rare neurogenetic disorder that affects approximately one in 15,000 people - about 500,000 individuals worldwide.Children and adults with AS typically have balance issues, motor impairment, and. Colin Farrell and ex-girlfriend Kim Bordenave petitioned to be co-conservators of their 17-year-old son James, according to a document obtained by Us Weekly. James, who was born in 2003, has been. Angelman Syndrome: Close to a cure? Rebecca Burdine knew something was wrong the day her baby girl was born. Sophie was born without a natural sucking reflex, making it nearly impossible to eat. Later, it became clear that she had hardly any muscle strength at all. As the months passed, Burdine, a developmental biologist from Princeton. Angelman syndrome may first be suspected in infants due to gross delay of motor milestones and/or speech delay. A physiotherapist may consider a diagnosis of Angelman syndrome based upon a detailed patient history, a thorough clinical evaluation and identification of characteristic findings

Sandbox Moments Life with our adult son with Angelmanwaardenburg syndrome famous people

DEFINITION Angelman Syndrome is a complex neurogenetic disorder that primarily affects the nervous system. Characteristic features of this condition include delayed development, intellectual disability, severe speech impairment, and problems with movement and balance (ataxia). Most affected children also have recurrent seizures (epilepsy) and a. The Angelman community has some extraordinary events lined up for you to participate in - together, we will make this amazing. Celebrity Awareness Launch. On February 13 th, several celebrities will take to social media to raise awareness about Angelman syndrome and show their support for FAST. They will post videos and tweets that may very.

'When he took his first steps, I nearly broke in half

Colin Farrell's Son Has Angelman Syndrome—Here's What That I

A person with Angelman syndrome will have a near-normal life expectancy, but they will need support throughout their life. Characteristics of Angelman syndrome. A child with Angelman syndrome will begin to show signs of delayed development at around 6 to 12 months of age, such as being unable to sit unsupported or make babbling noises Sotos syndrome is a genetic disorder, described in 1964, characterized by excessive growth before and after birth, a large, elongated (dolichocephalic) head, distinctive facial configuration, and a non-progressive neurological disorder with intellectual disability. Advanced bone age is present in approximately 75 to 85% of patients Angelman Syndrome is a genetic disorder of chromosome 15 characterised by severe intellectual disability, lack of speech, sleep disturbance, and yet, usually a happy demeanour. Affecting 1 in every 20,000-25,000 people and based on our population there are currently approximately 350 people living with AS in Ireland. Learn More. Angelman.

Angelman Syndrome - Story of Jane Villemoe

Angelman syndrome is a rare genetic disorder characterized by significant developmental and intellectual disability, movement problems, seizures, sleep irregularities, and an atypically happy demeanor. Once referred to as happy puppet syndrome (a term now considered a pejorative), the condition affects one of every 15,000 births, according to. Angelman syndrome causes developmental delays and is characterised by problems with speech and balance, and, at times, seizures. In legal documents obtained by The Blast, Farrell and Bordenave state that James requires daily assistance, which includes food preparation and getting dressed, and general monitoring of his health and wellbeing

Angelman Syndrome - Symptoms, Pictures, Causes, Life

Klinefelter syndrome is a genetic condition that results when a boy is born with an extra copy of the X chromosome. Klinefelter syndrome is a genetic condition affecting males, and it often isn't diagnosed until adulthood. Klinefelter syndrome may adversely affect testicular growth, resulting in smaller than normal testicles, which can lead to. GeneReviews, an international point-of-care resource for busy clinicians, provides clinically relevant and medically actionable information for inherited conditions in a standardized journal-style format, covering diagnosis, management, and genetic counseling for patients and their families.Each chapter in GeneReviews is written by one or more experts on the specific condition or disease and. 4 Famous People With Williams Syndrome #1 Ben (Big Red) Monkaba. Ben is a regular member of the Black Cat community theater ensemble with 3 shows to his credit. He has undergone multiple spine and cardiovascular surgeries, and he knows how important a few laughs and genuine smiles can be to a child in the hospital. #2 Leah War


Twelve studies regarding ASD in PWS and AS were reviewed. It was noteworthy that among the genetically confirmed UPD and DEL cases of PWS and AS, the rate of ASD was 25.3% (38/150; range 0-36.5%) in PWS and 1.9% in AS (2/104; range 0-100%) (Fisher's exact P<0.0001). Among the subset of cases with confirmed UPD or DEL, the rate of ASD in the UPD. Asperger's Syndrome, a form of Autism Spectrum Disorder, is a developmental disorder. Young people with Asperger's Syndrome have a difficult time relating to others socially and their behavior and thinking patterns can be rigid and repetitive. They also may have trouble understanding body language Angelman syndrome is caused due to absence or inactivation of the UBE3A gene. These problems associated with the UBE3A gene can be due to the following genetic mechanisms (1) (2) . Chromosome deletion: About 70-75% of cases of Angelman syndrome are caused by deletion of the region of maternal chromosome 15 containing the UBE3A gene